We're one step closer to heart disease.

我们在心脏病领域又迈进一步。

Yet another example close to heart.

再举个身边的事例。

I took it too close to heart and stop going to school, too.

我太在意了 也不去上学了。

Instead, hold the bitten limb below or close to heart level.

相反，将被咬伤的肢体放在心脏水平以下或靠近心脏水平。

At 7: 01, I'm closing my heart to you forever.

一过七点 我的心门从此就会对你紧闭。

Look, Chuck, sleep with every Nadine in town for all I care, but don't close your heart to Lily.

听着 恰克，你跟城里多少个纳丁上床我都不在乎，但别对莉莉紧闭心扉。

The other affair, that of his parting with his land, she did not take so close to heart, but her husband was indignant at such folly, and demanded that she influence her brother to abandon the attempt.

另一件事，就是他放弃自己的土地，她并没有那么在意，但她的丈夫对这种愚蠢行为感到愤怒，并要求她影响她的兄弟放弃这一企图。