We can’t close ourselves off from those opportunities.

我们不能将自己隔绝在这些机遇之外。

You could be really closed off, hard.

你也会封闭自己 冷酷无情。

Roads to the prison have been closed off.

通往这座监狱的道路已被封锁。

So Hawaii was still closed off.

所以夏威夷仍然是封闭的。

Soon after, his throat closed off.

很快，他的嗓子就堵住了。

The barrier island was closed off Thursday as the storm approached.

周四，由于风暴来袭，这座堰洲岛被封锁。

But the town has effectively been closed off from the outside world.

但该镇实际上已与外界隔绝。

This will help thicken their skin and close off any small cuts.

这将有助于土豆皮变厚以及封闭土豆任何小的破损处。

The city closed off nursing homes since January 27 amid challenges from the novel coronavirus.

由于新冠病毒带来的挑战，北京市于1月27日对养老院进行了封闭管理。

" The designation of the cooperative Caruna closes off another tool of the regime" .

" 将国家农村基金合作社指定为制裁对象，阻断了奥尔特加政权的另一个工具。"

But, paradoxically, the basis for this joy lies in closing ourselves off from life.

但是，矛盾的是，这种快乐的基础在于将我们自己与生活隔绝。

Board can also mean closing off parts of a building with pieces of wood.

Board也可以指用木片将建筑物的某些部分封闭起来。

Feeling disgust ensures that we literally physically close ourselves off and avoid those things.

感到厌恶让我们不愿靠近那些东西。

They have also closed off the bridges over the River Tigris with concrete barriers.

他们还用混凝土障碍物封锁了底格里斯河上的桥梁。

And, O'Malley? Close off the gallery. We don't need an audience for this.

O'Malley，还有件事？把观察室关掉。我们不需要观众。

Yes, sir. When it overturned, that iceberg closed off every exit.

“是的，先生。冰山翻倒的时候把所有的出口都堵住了。”

Having that ability to close off a chapter and move on is really, really important.

结束一个章节并且继续向前的能力非常重要。

Honestly I closed myself off to a world of expression that I never really knew existed.

老实说，我把自己封闭到一个我从来都不知道存在的世界里。

He says about 1200 fighters remain are using ammunition smuggled into now closed off by soldiers.

他表示，剩下的1200名武装人员用走私得来的弹药进行抵抗，现在他们已经被警察封锁了。

The routes that ISIS took or encouraging their followers to take may not have been closed off.

ISIS采取或鼓励其追随者走的路线可能并没有被关闭。