Repeated bouts of acute pancreatitis can progress to chronic pancreatitis.

反复发作的急性胰腺炎也可进展为慢性胰腺炎。

Early diagnosis of chronic pancreatitis is challenging.

慢性胰腺炎的早期诊断比较困难。

Importantly, cystic fibrosis is the main cause of chronic pancreatitis in children.

有一点很重要，即囊性纤维化是儿童慢性胰腺炎的主要病因。

Chronic pancreatitis is inflammation due to irreversible changes to the pancreatic structure, like fibrosis, atrophy and calcification.

慢性胰腺炎是胰腺结构发生不可逆改变导致的炎症，例如纤维化、萎缩和钙化。

While a history of acute pancreatitis might lead to chronic pancreatitis, these diseases have distinct histopathologies.

尽管急性胰腺炎可能导致慢性胰腺炎的发生，但这两种疾病有各自不同的组织病理学特点。

This gradual process of healthy pancreatic tissue getting replaced by misshaped ducts, fibrosis, and calcium deposits is chronic pancreatitis.

健康的胰腺组织逐渐被畸形的导管、纤维组织和钙沉积物取代，这个渐进性的过程就是慢性胰腺炎。

People with chronic pancreatitis often have continuous or intense intermittent abdominal pain in the epigastric region, that sometimes radiates to the back.

慢性胰腺炎患者通常会有持续的或者剧烈的间歇性上腹痛，有时也会放射到背部。

In addition to alcohol abuse, other known causes of acute pancreatitis that frequently turn into chronic pancreatitis include tumors, trauma to the pancreas, and cystic fibrosis.

除了酒精滥用之外，其它已知的常会导致急性胰腺炎转为慢性胰腺炎的因素，包括肿瘤、胰腺外伤和囊性纤维化。

Treatment of chronic pancreatitis involves controlling pain and trying to control the risk factors —things like drinking less alcohol, eating less meat, and reducing obesity.

慢性胰腺炎的治疗包括止痛和尽量避免危险因素：少喝酒、少吃肉、减肥！

Alright as a quick recap, chronic pancreatitis happens when irreversible changes to the pancreatic structure, like fibrosis, atrophy and calcification begin to decrease the functions of the organ.

得！快速回顾一下：当胰腺结构发生不可逆改变（如纤维化、萎缩和钙化）造成器官功能开始减退时，慢性胰腺炎发生。

A long-term consequence of chronic pancreatitis is the development of diabetes mellitus, which happens as the recurrent inflammation begins to damage the alpha and beta cells of the pancreas.

慢性胰腺炎的一个长期后果是糖尿病，这通常是由于反复发作的炎症开始损害胰腺的α和β细胞。

Even though elevated lipase and amylase levels are suggestive of acute pancreatitis, in chronic pancreatitis there may not be enough healthy pancreatic tissue to make those enzymes, so they may or may not be elevated.

尽管脂肪酶和淀粉酶水平升高提示有急性胰腺炎，但在慢性胰腺炎中因为可能没有足够多健康的胰腺组织产生这两种酶，所以它们不一定升高。