Nondisjunction

（重定向自Chromosomal nondisjunction）

Nondisjunction of sister chromatids during mitosis:
Left: Metaphase of mitosis. Chromosome line up in the middle plane, the mitotic spindle forms and the kinetochores of sister chromatids attach to the microtubules.
Right: Anaphase of mitosis, where sister chromatids separate and the microtubules pull them in opposite directions.
The chromosome shown in red fails to separate properly, its sister chromatids stick together and get pulled to the same side, resulting in mitotic nondisjunction of this chromosome.

Karyotype of X monosomy (Turner syndrome) This condition is characterized by the presence of only one X chromosome and no Y chromosome (see bottom right corner).

Karyotype of trisomy 21 (Down syndrome)
Note that chromosome 21 is present in 3 copies, while all other chromosomes show the normal diploid state with 2 copies. Most cases of trisomy of chromosome 21 are caused by a nondisjunction event during meiosis I (see text).

Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate properly during cell division. There are three forms of nondisjunction: failure of a pair of homologous chromosomes to separate in meiosis I, failure of sister chromatids to separate during meiosis II, and failure of sister chromatids to separate during mitosis. Nondisjunction results in daughter cells with abnormal chromosome numbers (aneuploidy).

单词	Chromosomal nondisjunction
释义	Chromosomal nondisjunction 英语百科 Nondisjunction （重定向自Chromosomal nondisjunction） Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate properly during cell division. There are three forms of nondisjunction: failure of a pair of homologous chromosomes to separate in meiosis I, failure of sister chromatids to separate during meiosis II, and failure of sister chromatids to separate during mitosis. Nondisjunction results in daughter cells with abnormal chromosome numbers (aneuploidy).
随便看	desitometer的意思 desitometric titration的意思 Desitriptilina的意思 desitriptillna的意思 Desitriptyline的意思 De Sitter的意思 Desitter的意思 de Sitter model的意思 de sitter solution的意思 De Sitter space的意思 de sitter space time的意思 De Sitter universe的意思 de Sitter, Willem的意思 desity airspeed的意思 desivac的意思 desivac process的意思 desivering bath的意思 Desivon的意思 desizability的意思 desize的意思 desized cloth的意思 desized cotton的意思 desizer的意思 desizing的意思 de sizing的意思