芝加哥期货交易所（英文：Chicago Board of Trade，缩写：CBOT）是美国芝加哥的期货交易所，成立于1848年是世界上最古老的期货和期权交易所。旗下有50种以上期货和期权产品总计3600个项目和商品，芝加哥商品交易所和三个其他交易所（芝加哥期货交易所，纽约商业交易所，纽约商品交易所）现在都是CME集团旗下子公司。

1864年，芝加哥期货交易所上市首个标准化的“交易所买卖”远期合约，这被称为期货合约。1919年，芝加哥黄油和鸡蛋委员会脱离芝加哥期货交易所进行了重组，使会员交易未来的贸易价差之类的金融避险商品，之后更名为芝加哥商品交易所。

The Chicago Board of Trade (CBOT), established in 1848, is one of the world's oldest futures and options exchange. More than 50 different options and futures contracts are traded by over 3,600 CBOT members through open outcry and electronic trading. Volumes at the exchange in 2003 were a record breaking 454 million contracts. On 12 July 2007, the CBOT merged with the Chicago Mercantile Exchange (CME) to form the CME Group, a CME/Chicago Board of Trade Company. CBOT and three other exchanges (CME, NYMEX, and COMEX) now operate as designated contract markets (DCM) of the CME Group.