They call it the CFTR gene because it's a chlorine transport.

他们称其为CFTR基因，它负责氯的转运。

Cystic fibrosis is caused by mutation in CFTR.

囊性纤维化是由 CFTR 突变引起的。

A new hope for patients with CF has been the development of personalized treatments that target specific CFTR mutation types.

CF患者的新希望是个体化治疗的发展，它可以聚焦到特定的CFTR突变类型。

In fact, the term cystic fibrosis refers to the pancreatic cysts and fibrosis that develop in patients with mutations in the CFTR gene.

事实上，“囊性纤维化”这个概念是指在CFTR基因突变患者中发生的胰腺囊肿和纤维化。

Lack of a working CFTR gene results in the mucus produced by cells lining the airways of the lungs being too thick.

缺乏有效的 CFTR 基因会导致肺部气道内壁细胞产生的粘液太稠。

CF is an autosomal recessive disorder involving the CFTR gene, which stands for " cystic fibrosis transmembrane conductance regulator, " and this gene codes for the CFTR protein.

CF是一种常染色体隐形遗传病，涉及CFTR基因；CFTR代表跨膜传导调节基因，它编码了CFTR蛋白。

CF develops when there's a mutation in the CFTR gene, but because it's autosomal recessive, you need to inherit two mutated CFTR genes, one from mom and one from dad.

CFTR基因突变时会产生CF，但它是常染色体隐形遗传的；患者体内两条CFTR突变基因，一条来自母亲，另一条来自父亲。

The CFTR protein is a channel protein that pumps chloride ions into various secretions, those chloride ions help draw water into the secretions, which ends up thinning them out.

CFTR蛋白是一种可以将氯离子泵入分泌物的通道蛋白，氯离子可以使水分渗入分泌物，对它们进行稀释。

The first is in transforming understanding of cystic fibrosis, an illness caused by a person inheriting two broken versions of a gene called CFTR, one from each parent.

第一个是转变对囊性纤维化的理解， 囊性纤维化是一种疾病，由一个人继承了一个名为 CFTR 的基因的两个损坏版本引起，每个版本来自父母双方。

Time for a quick recap: cystic fibrosis is an autosomal recessive disorder involving the CFTR gene, which most notably causes issues with the lungs and the pancreas, but can also affect other organs.

得！快速回顾一下：囊性纤维化是一种常染色体隐形遗传病，与CFTR基因有关，在肺和胰腺组织中病变最为显著，但也可以影响其他器官。