CAAT box

The left model is of the complex of NF-YC/NF-YB with
the CCAAT element from the pro- 2(I) collagen promoter. The DNA backbone is shown as ribbons (purple) with the bases displayed. The two
possible locations of the CCAAT box, according to the modeling, have been colored cyan. For the right model of the NF-Y/CCAAT complex. NF-YC, NF-YB
and DNA are colored as in figure on the left, whereas NF-YA is colored blue. The two alternative positions for the linker connecting NF-YA1 and NF-YA2
sub-domains are shown as blue dotted lines. Secondary structure elements of the histone pair that are implicated in NF-YA1 and NF-YA2
recognition (see text) are labeled and colored in red and gray, respectively. For clarity, only the bases for the CCAAT pentanucleotide are shown
and labeled.[1]

In molecular biology, a CCAAT box (also sometimes abbreviated a CAAT box or CAT box) is a distinct pattern of nucleotides with GGCCAATCT consensus sequence that occur upstream by 60-100 bases to the initial transcription site. The CAAT box signals the binding site for the RNA transcription factor, and is typically accompanied by a conserved consensus sequence. It is an invariant DNA sequence at about minus 70 base pairs from the origin of transcription in many eukaryotic promoters. Genes that have this element seem to require it for the gene to be transcribed in sufficient quantities. It is frequently absent from genes that encode proteins used in virtually all cells. This box along with the GC box is known for binding general transcription factors. Both of these consensus sequences belong to the regulatory promoter. Full gene expression occurs when transcription activator proteins bind to each module within the regulatory promoter. Protein specific binding is required for the CCAAT box activation. These proteins are known as CCAAT box binding proteins/CCAAT box binding factors.

单词	CAT box
释义	CAT box 原声例句摩登家庭第十季_Modern Family-Season10 No, I used Larry's cat box for fun. 你说呢？我用猫砂上厕所是为了好玩吗。学习充电站 I went around and mentally mapped out the space, making sure I had a clear image of the layout, where the furniture was, and whether or not I needed to change my cat's litter box, which, it turns out, I did. 我在里面转了一圈，在脑海里勾勒出整个空间的地图，确定自己对公寓布局有了一副清晰的图像，家居在什么位置，是否需要把猫窝挪个地方，事实上，我也那么做了。英语百科 CAAT box In molecular biology, a CCAAT box (also sometimes abbreviated a CAAT box or CAT box) is a distinct pattern of nucleotides with GGCCAATCT consensus sequence that occur upstream by 60-100 bases to the initial transcription site. The CAAT box signals the binding site for the RNA transcription factor, and is typically accompanied by a conserved consensus sequence. It is an invariant DNA sequence at about minus 70 base pairs from the origin of transcription in many eukaryotic promoters. Genes that have this element seem to require it for the gene to be transcribed in sufficient quantities. It is frequently absent from genes that encode proteins used in virtually all cells. This box along with the GC box is known for binding general transcription factors. Both of these consensus sequences belong to the regulatory promoter. Full gene expression occurs when transcription activator proteins bind to each module within the regulatory promoter. Protein specific binding is required for the CCAAT box activation. These proteins are known as CCAAT box binding proteins/CCAAT box binding factors.
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