腺苷高半胱氨酸酶（英语：Adenosylhomocysteinase）是一个将S-腺苷高半胱氨酸转变为高半胱氨酸与腺苷的酶。

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Adenosylhomocysteinase (EC3.3.1.1, S-adenosylhomocysteine synthase, S-adenosylhomocysteine hydrolase, adenosylhomocysteine hydrolase, S-adenosylhomocysteinase, SAHase, AdoHcyase) is an enzyme that converts S-adenosylhomocysteine to homocysteine and adenosine. This enzyme catalyses the following chemical reaction