Camajuaní is a municipality and town in the Villa Clara Province of Cuba.

In 1819 was decided the construction of a new port in near Caibarién to replace an old one located in Tesisco. From that moment, settlers established in the surroundings creating a new village. In 1832 blueprints for the new town of Caibarien were presented, and finally in 1841 this city was founded. Consequently in 1864 an extension of the railway was planned in order to bring the sugar from the Camajuani valley to Caibarien and a new settlement began near the train station. This is the starting point and birth of Camajuaní village.