冠状动脉旁路移植（英语：Coronary artery bypass surgery，常缩写为CABG），又称冠脉搭桥或搭桥，即冠状动脉旁路移植术，是一项缓解心绞痛和减少冠心病死亡风险的手术。搭桥所用的动脉或静脉均来自患者自身（乳内动脉、桡动脉、胃网膜右动脉、大隐静脉）。将血管桥接于冠状动脉，以绕过冠脉粥样硬化狭窄部，从而提高冠脉灌注，增加心肌氧供。这项手术通常在心脏停搏下进行，需使用体外循环支持; 而搭桥手术也可在跳动的心脏上进行，所谓的“非体外循环（off-pump）”手术。

Coronary artery bypass surgery, also known as coronary artery bypass graft (CABG, pronounced "cabbage") surgery, and colloquially heart bypass or bypass surgery, is a surgical procedure consisting of either diverting the left internal thoracic artery (left internal mammary artery or "LIMA") to the left anterior descending (LAD) branch of the left main coronary artery; or a harvested great saphenous vein of the leg, attaching the proximal end to the aorta or one of its major branches, and the distal end to immediately beyond a partially obstructed coronary artery (the "target vessel") - usually a 50% to 99% obstruction. The purpose is to restore normal blood flow to that partially obstructed coronary artery. It is performed to relieve angina unsatisfactorily controlled by maximum tolerated anti-ischemic medication, prevent or relieve left ventricular dysfunction, and/or reduce the risk of death. It does not prevent heart attacks. This surgery is usually performed with the heart stopped, necessitating the usage of cardiopulmonary bypass; however, two alternative techniques are also available allowing CABG to be performed on a beating heart either without using the cardiopulmonary bypass deemed as "off-pump" surgery or performing beating surgery using partial assistance of the cardiopulmonary bypass called as "on-pump beating" surgery. The latter gathers the advantages of the on-pump stopped and off-pump while minimizing their respective side-effects.