布赖顿旅馆爆炸案是1984年10月12日凌晨2:54（GMT），发生于英国海滨旅游胜地布赖顿的Grand酒店的一次临时派爱尔兰共和军组织的爆炸案。当时执政的保守党高级官员们正在那里召开年会。虽然警备森严，仍有2枚巨大的炸弹在此爆炸。有5个人在爆炸中死亡（包括安东尼Berry爵士和约翰Wakeham的前妻Roberta），但没有一名英国内阁成员死亡。首相撒切尔夫人还在准备演说，得以幸免，但政府其他成员重伤——贸易及工业大臣谭百德（Norman Tebbit）的妻子也受伤瘫痪。

爱尔兰共和军次日宣布对此事件负责，说他们要再干一次，其声明中的一句话也随之出名：

The Brighton hotel bombing occurred on 12 October 1984 at the Grand Hotel in Brighton, England. A long-delay time bomb was planted in the hotel by Provisional Irish Republican Army (IRA) member Patrick Magee, with the purpose of killing Prime Minister Margaret Thatcher and her cabinet, who were staying at the hotel for the Conservative Party conference. Although Thatcher narrowly escaped injury, five people were killed, including two high-profile members of the Conservative Party, and 31 were injured.