威廉大街（德语：Wilhelmstraße）是德国首都柏林市中心的一条街道，从19世纪中叶到1945年，这里一直是行政中心，先是普鲁士王国，然后是统一的德国，帝国总理府和德国外交部。因此，“威廉大街”在德国常用来代表德国政府，如同“白厅”经常被用来代表英国政府；在英语中，威廉大街通常代表德国外交部。

威廉大街的路线，从菩提树下大街向南略微偏东，直到Hallesches Ufer附近的 Stresemannstrasse路口，长约2公里。交汇道路有 Behrenstrasse、莱比锡大街和Zimmerstrasse，威廉大街以西名为Niederkirchnerstrasse（二战前称为阿布雷契亲王大街）。

Wilhelmstrasse (German:Wilhelmstraße, see ß) is a major thoroughfare in the central Mitte and Kreuzberg districts of Berlin, Germany. Until 1945, it was recognised as the centre of the government, first of the Kingdom of Prussia, later of the unified German Reich, housing in particular the Reich Chancellery and the Foreign Office. The street's name was thus also frequently used as a metonym for overall German governmental administration, much as the term "Whitehall" is often used to signify the British governmental administration as a whole; in English, "the Wilhelmstrasse" usually referred to the German Foreign Office.