维尔纳综合症（Werner syndrome，缩写WS）又称成人早衰症，是一种极为罕见的常染色体隐性遗传性早衰症，1904年由德国人 Otto Werner 首先报道，患者位于8号染色体短臂的、编码DNA螺旋酶的WRN基因有缺陷，患者体细胞端粒比一般人的端粒以更快的速度变短，导致在青春期后迅速衰老，出现矮身材、脱发、白发、声音嘶哑、皮肤角化、关节僵硬、肌肉萎缩、白内障等症状。

目前对于该病尚无特殊治疗方法。

Werner syndrome (WS), also known as "adult progeria", is a rare, autosomal recessive progeroid syndrome (PS), which is characterized by the appearance of premature aging.

Werner syndrome is named after the German scientist Otto Werner. He identified the syndrome in four siblings observed with premature aging, which he explored as the subject of his dissertation of 1904.