大乌斯秋格 （俄语：Вели́кий У́стюг）是俄罗斯沃洛格达州东北部的一个城市，位于尤克河与苏霍纳河汇成北德维纳河之处，距沃洛格达450公里。2002年人口33,419人。

1207年首见于文献，1708年设市。俄国三位早期探险家谢苗·迭日涅夫、叶罗费·帕夫洛维奇·哈巴罗夫、弗拉基米尔·阿特拉索夫都出生于此。

Veliky Ustyug (Russian:Вели́кий У́стюг) is a town in Vologda Oblast, Russia, located in the northeast of the oblast at the confluence of the Sukhona and Yug Rivers. As of the 2010 Census, its population was 31,665.

Veliky Ustyug has a great historical significance and was one of the major cities of the Russian North. It preserved some of the past urban structure and many of the architectural monuments, it was completely deprived of its leading role and is now merely a tourist attraction.