Vedolizumab

Vedolizumab (trade name Entyvio) is a monoclonal antibody developed by Millennium Pharmaceuticals, Inc (a subsidiary of Takeda Pharmaceuticals) for the treatment of ulcerative colitis and Crohn's disease. It binds to integrin α₄β₇ (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1). Blocking the α₄β₇ integrin results in gut-selective anti-inflammatory activity. It is marketed under the trade name Entyvio.

单词	Vedolizumab
释义	Vedolizumab 英语百科 Vedolizumab Vedolizumab (trade name Entyvio) is a monoclonal antibody developed by Millennium Pharmaceuticals, Inc (a subsidiary of Takeda Pharmaceuticals) for the treatment of ulcerative colitis and Crohn's disease. It binds to integrin α₄β₇ (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1). Blocking the α₄β₇ integrin results in gut-selective anti-inflammatory activity. It is marketed under the trade name Entyvio.
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