J节段 V(D)J recombination
(重定向自VDJ recombination)
J节段 (连接节段) 是免疫球蛋白和T细胞受体基因座中的编码串行。J节段介于可变基因节段(V) 和恒定基因节段(C) 之间。
单词 | VDJ recombination |
释义 |
VDJ recombination
中文百科
J节段 V(D)J recombination(重定向自VDJ recombination)
J节段 (连接节段) 是免疫球蛋白和T细胞受体基因座中的编码串行。J节段介于可变基因节段(V) 和恒定基因节段(C) 之间。
英语百科
V(D)J recombination J节段(重定向自VDJ recombination)
![]() V(D)J recombination, less commonly known as somatic recombination, is the unique mechanism of genetic recombination that occurs only in developing lymphocytes during the early stages of T and B cell maturation. The process results in the highly diverse repertoire of antibodies/immunoglobulins (Igs) and T cell receptors (TCRs) found on B cells and T cells, respectively. The process is a defining feature of the adaptive immune system and its development was a key event in the evolution of jawed vertebrates. |
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