荒漠巨蜥（Varanus griseus），又名沙漠巨蜥，是北非及亚洲西部的巨蜥。

荒漠巨蜥体长1呎10吋，尾巴长2呎4吋，牙齿尖锐。吻端凹陷，鼻孔斜开，较接近眼窝。脚趾较短，尾巴圆或稍为扁平。头部的鳞片非常细小，背部鳞片细小及光滑。在颈部两侧的鳞片呈锥形。腹部鳞片光滑，共有110-125行。牠们呈灰黄色，或多或少有一些褐色的斑纹。幼蜥有黄色圆点及深褐色的斑纹。

The desert monitor, Varanus griseus, is a species of monitor lizards of the order Squamata found living throughout North Africa and Central and South Asia. Three subspecies have been described:

The desert monitor is carnivorous, feeding on a wide range of vertebrates and invertebrates.