明尼苏达大学双城分校（英语：University of Minnesota, Twin Cities），是位于美国明尼苏达州双城区（即明尼阿波利斯及圣保罗）的一所公立大学，为明尼苏达大学系统历史最悠久，规模最大的分校，常被直接称为明尼苏达大学。它是美国最著名的公立研究型大学之一，也是世界一流的学术研究机构，在2011年上海交通大学世界大学学术排名评比为全球第28名，学校亦有公立常春藤之称。

明尼苏达大学是美国知名的十大联盟的成员大学之一，亦是美国最具综合性的高等学府之一，位居最富盛名的大学之列，具有优秀的教育和服务社会的传统。

The University of Minnesota Twin Cities (Minnesota; locally known as the U of M or simply the U) is a public research university located in Minneapolis and St. Paul, Minnesota. The Minneapolis and St. Paul campuses are approximately 3 miles (4.8 km) apart, and the Saint Paul campus is actually in neighboring Falcon Heights. It is the oldest and largest campus within the University of Minnesota system and has the sixth-largest main campus student body in the United States, with 51,147 students in 2013–14. The university is organized into 19 colleges and schools, and it has sister campuses in Crookston, Duluth, Morris, and Rochester. UMN is categorized as an R1 Doctoral University with the (highest research activity) in the Carnegie Classification of Institutions of Higher Education.