Torcetrapib

![Torcetrapib synthesis: U.S. Patent 6,313,142 Also see:[21][22]](/uploads/202502/17/Torcetrapib_synthesis.svg2540.png)
Torcetrapib (CP-529,414, Pfizer) was a drug being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease. Its development was halted in 2006 when phase III studies showed excessive all-cause mortality in the treatment group receiving a combination of atorvastatin (Lipitor) and torcetrapib.