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单词 Tetraethyl pyrophosphate
释义

Tetraethyl pyrophosphate

中文百科

焦磷酸四乙酯

Ball-and-stick model

焦磷酸四乙酯TEPP)简称特普,是一种含磷的有机化合物,是焦磷酸酯的衍生物,是一种无色有吸湿性的剧毒液体。是由法国化学家菲利普·克莱蒙所合成,是最早发现含有磷的乙酰胆碱酯酶抑制剂。

焦磷酸四乙酯是透明无色的液体,可溶于水,但在水中会迅速水解。可以用二当量的氯磷酸二乙酯和一当量的水反应来制备焦磷酸四乙酯.反应中需加入吡啶来中和反应产生的氯化氢

此有机化合物已被用作杀虫剂,杀螨剂和杀鼠剂。商品名包括Grisol、Fosvex、Lirohex、Killax、Mortopal、Nifost、Tetraspa、Tetron和Vapotone。特普不是欧盟授权使用的化学物质。在美国已撤回含特普产品的许可。

英语百科

Tetraethyl pyrophosphate 焦磷酸四乙酯

Skeletal formula
Ball-and-stick model
Synthesis of TEPP according to De Clermont and Moschnin
Synthesis TEPP according to Toy

Tetraethyl pyrophosphate, abbreviated TEPP, is an organophosphate compound, which is used as an insecticide. This compound is a clear, colorless liquid, which is soluble in water, but hydrolyzes rapidly. There are several mechanism by which TEPP can be synthesized and it was first synthesized by Philippe de Clermont and Muscovite Wladimir Moschnin in 1854. It is a toxic compound, due to its anticholinesterase activity, which not only applies to insects, but also to other animals. TEPP is metabolized with the assistance of many different enzymes en the metabolistes are excreted via the urine.

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更新时间:2025/6/17 20:42:45