We have certain medicines now that target certain mutations in lung cancer where the majority of patients have benefit and their tumors shrink.

我们现在有某些药物针对肺癌的某些突变，大多数患者都从中受益并且他们的肿瘤缩小了。

And so how effective are these drugs when they target a specific mutation, instead of a specific region of the body that the cancer is coming from?

那么，当这些药物针对特定突变而不是癌症来源的特定身体区域时，它们的效果如何？

What these new types of studies are really asking is whether we can target specific mutations which are mistakes in the genes that arise in tumors and treat them the same even if they come from different organs.

这些新型研究真正要问的是，我们是否可以针对肿瘤中出现的基因错误的特定突变进行治疗，即使它们来自不同的器官。