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单词 T4 DNA ligase
释义

T4 DNA ligase

英语百科

DNA ligase

A pictorial example of how a ligase works (with sticky ends)

In molecular biology, DNA ligase is a specific type of enzyme, a ligase, (EC6.5.1.1) that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond. It plays a role in repairing single-strand breaks in duplex DNA in living organisms, but some forms (such as DNA ligase IV) may specifically repair double-strand breaks (i.e. a break in both complementary strands of DNA). Single-strand breaks are repaired by DNA ligase using the complementary strand of the double helix as a template, with DNA ligase creating the final phosphodiester bond to fully repair the DNA.

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更新时间:2025/6/23 10:39:27