Controlled ovarian hyperstimulation
![Nomogram for the starting dosage of FSH preparation as estimated from age, antral follicle count (AFC) and endogenous serum FSH taken day 3 of the menstrual cycle.[5] An example is given in the nomogram, wherein an age of 32 years and an AFC of 12 gives a point on the middle line that, when continued to an FSH of 5 IU/l, results in a starting FSH dosage of almost 200 IU/l.](/uploads/202502/14/Nomogram_for_FSH_dosage_by_AFC5703.png)
![Nomogram for the starting dosage of FSH as estimated from age, anti-Müllerian hormone (AMH) and endogenous serum FSH taken day 3 of the menstrual cycle (same as previous nomogram but with AMH istead of AFC).[5]](/uploads/202502/14/Nomogram_for_FSH_dosage_by_AMH5703.png)
Controlled ovarian hyperstimulation is a technique used in assisted reproduction involving the use of fertility medications to induce ovulation by multiple ovarian follicles. These multiple follicles can be taken out by oocyte retrieval (egg collection) for use in in vitro fertilisation (IVF), or be given time to ovulate, resulting in superovulation which is the ovulation of a larger-than-normal number of eggs, generally in the sense of at least two. When ovulated follicles are fertilised in vivo, whether by natural or artificial insemination, there is a very high risk of a multiple pregnancy.