SSRIs simply don't work for all patients.

SSRIs 并不适用于所有患者。

Be it prescription SSRIs labels that excuse irrational behavior or passive therapies.

要么是通过开处方抗抑郁药来应对其非理性行为，要么就是进行被动疗法。

SSRIs reduce the reuptake of serotonin, which increases the amount of serotonin hanging around synapses.

SSRIs 减少了对 5-羟色胺的再摄取，从而增加了突触周围的 5-羟色胺含量。

Some of the most commonly used medications for depression are selective serotonin reuptake inhibitors, or SSRIs.

一些最常用的抑郁症治疗药物是选择性 5-羟色胺再摄取抑制剂或 SSRIs。

Which may be one reason why SSRI medications typically take so long to work.

这也许是 SSRI 药物通常需要很长时间才能起作用的一个原因。

SSRI's help regulate serotonin levels in the brain, while SNRIs help regulate serotonin, norepinephrine and dopamine, to manage anxiety.

SSRIs帮助调节大脑中5-羟色胺的水平，而SNRIs帮助调节5-羟色胺、去甲肾上腺素和多巴胺水平，以调节焦虑。

Another clue is that some drugs and medications can trigger manic episodes, like selective serotonin reuptake inhibitors (or SSRIs).

另一个线索则是，某些药物和治疗可以引起躁狂发作，比如选择性五羟色胺再摄取抑制剂（SSRIs）。

Most SSRIs are off-patent and therefore cheap.

大多数 SSRI 都没有专利，因此价格便宜。

That's right. SSRIs can help alleviate depression.

这是正确的。 SSRIs 有助于缓解抑郁症。

The key thing is this, SSRIs can help alleviate depression.

关键是，SSRIs 可以帮助缓解抑郁症。

Some doctors prescribe medications called SSRIs that are usually used for depression.

一些医生开出通常用于治疗抑郁症的称为 SSRI 的药物。

Even though serotonin concentrations may go up right away when you take an SSRI, it can still take weeks for people to start feeling better.

即使服用 SSRI 后 5-羟色胺浓度可能会立即升高，但仍然需要数周时间才能让患者感觉有所好转。

If that were true, you'd expect that SSRI medications to work pretty quickly, and to work for everyone with depression — but they don't.

如果这是真的，你会期望 SSRI 药物能很快发挥作用，并且对每个抑郁症患者都有效，但其实并不是这样。

Bulimia is sometimes also treated with antidepressant medications, like SSRIs or selective serotonin reuptake inhibitors, and typically a combination of therapy with the medication works best for severe cases.

暴食症有时会用抗抑郁药治疗，比如SSRIs，即五羟色胺再摄取抑制剂；通常，服药的同时接受心理治疗对重症患者疗效最好。

In terms of medications, antidepressants, in particular selective serotonin reuptake inhibitors (or SSRIs), can help to reduce depressive symptoms that often accompany PTSD, and can help minimize flashbacks and nightmares.

药物治疗方面，抗抑郁药，特别是选择性5-羟色胺再摄取抑制剂（SSRIs）能减轻PTSD伴随的抑郁症状，还能减少闪回和噩梦。

However, this belief in the ease of ending SSRI treatment was based on studies in which the patients had been on it for just a few weeks.

然而，这种认为结束 SSRI 治疗很容易的信念是基于对患者仅服用几周的研究。

It was the first of a new class of drugs called Selective Serotonin Reuptake Inhibitors, or SSRI's, which block the reabsorption of serotonin, leaving more available in the brain.

它是称为选择性 5- 羟色胺再摄取抑制剂或 SSRI 的新型药物中的第一种， 它可以阻止 5-羟色胺的再吸收， 从而在大脑中留下更多可用药物。

For a long time, stopping taking SSRIs was thought not to provoke withdrawal symptoms.Any symptom which did appear was seen, instead, as a sign of relapse into depression.

很长一段时间以来，人们认为停止服用 SSRIs 不会引起戒断症状。相反，任何确实出现的症状都被视为抑郁症复发的迹象。

For many years drug companies, the main source of research on SSRIs, tended not to publish in scientific journals the results of clinical trials that cast doubt on their products' utility.

多年来，作为 SSRIs 研究主要来源的制药公司往往不会在科学期刊上发表临床试验的结果，以免对其产品的效用产生怀疑。

At the moment, drug choice works by trial and error, with the initial SSRI being selected more or less at random and a replacement chosen a few weeks later if it does not do the business.

目前，药物选择是通过反复试验来进行的，最初的 SSRI 或多或少是随机选择的， 如果它不起作用， 则在几周后选择替代品。