南奥赛梯自治州（俄语：Юго-Осетинская автономная область、格鲁吉亚语：სამხრეთ ოსეთის ავტონომიური ოლქი、奥塞梯语：Хуссар Ирыстоны автономон бӕстӕ）是苏联的一个自治州，属于格鲁吉亚苏维埃社会主义共和国，创建于1922年。现在其领土有南奥赛梯共和国继承。

The South Ossetian Autonomous Oblast (Russian:Юго-Осетинская автономная область, Georgian:სამხრეთ ოსეთის ავტონომიური ოლქი, Ossetian: Хуссар Ирыстоны автономон бӕстӕ) was an autonomous oblast of the Soviet Union created within the Georgian SSR on April 20, 1922. Its autonomy was revoked on December 10, 1990 by the Supreme Soviet of the Georgian SSR, leading to the First South Ossetian War. Currently, its territory is controlled by the breakaway Republic of South Ossetia.