4-氨基水杨酸 4-Aminosalicylic acid
（重定向自Sodium aminosalicylate）
4-氨基水杨酸（英语：4-Aminosalicylic acid，又名对氨基水杨酸、氨基水杨酸或PAS）是一种用于治疗结核病的抗菌药。 它也被用于治疗炎症性肠病。 它通过抑制NF-κB及清除自由基而发挥作用。美沙拉嗪（5-氨基水杨酸）与4-氨基水杨酸十分相似，并同样具有药用。
加热后，4-氨基水杨酸会发生脱羧反应，分解成3-氨基苯酚和二氧化碳。
Sodium aminosalicylate
中文百科
英语百科
4-Aminosalicylic acid 4-氨基水杨酸
（重定向自Sodium aminosalicylate）
4-Aminosalicylic acid (para-aminosalicylic acid or PAS) is an antibiotic used to treat tuberculosis. This organic compound has also been use since the 1940s for the treatment of inflammatory bowel diseases (IBDs), where it has shown greater potency in ulcerative colitis and Crohn's disease. It is thought to act via NF-κB (nuclear factor-kappa B) inhibition and free radical scavenging. The closely related chemical compound 5-aminosalicylic acid, sold under the name mesalazine, also has medical uses.
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