" It retains memory." Social factors can also exacerbate the problem, with the negative emotional consequences of pain (including an inability to work, social alienation and depression) leading to activation of the very brain regions that can amplify its severity.

“它保留记忆。”社会因素也会加剧问题，疼痛带来的负面情绪后果（包括无法工作、社交疏远和抑郁）会导致大脑区域激活，从而加剧问题的严重性。