| 单词 | SNRPN |
| 释义 |
SNRPN
原声例句
Osmosis-遗传 Among these are SNRPN which stands for Small Nuclear Ribonucleoprotein Polypeptide N and a cluster of snoRNAs, which stands for small nucleolar RNAs; these genes all have protein products that modify other RNAs. 这些基因包括SNRPN基因，即小核核糖核蛋白多肽N基因，以及snoRNAs（核仁小RNA基因簇）；这些基因的蛋白产物可以修饰其它RNA。
英语百科
Small nuclear ribonucleoprotein polypeptide N（重定向自SNRPN）
  Small nuclear ribonucleoprotein-associated protein N is a protein that in humans is encoded by the SNRPN gene. The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Prader-Willi syndrome due to parental imprint switch failure. |
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