Translocations can disrupt SNRNP and move the small nucleolar RNA genes away from their imprinting center, causing them to get methylated and turned off.
SNRNP基因易位会破坏小核内核糖核蛋白（SNRPN），并将核仁小RNA基因移出印记中心，导致这些基因的甲基化沉默。
Small nucleolar RNA
原声例句
Osmosis-遗传
Osmosis-遗传
Among these are SNRPN which stands for Small Nuclear Ribonucleoprotein Polypeptide N and a cluster of snoRNAs, which stands for small nucleolar RNAs; these genes all have protein products that modify other RNAs.
这些基因包括SNRPN基因，即小核核糖核蛋白多肽N基因，以及snoRNAs（核仁小RNA基因簇）；这些基因的蛋白产物可以修饰其它RNA。
中文百科
核仁小核糖核酸
小核仁RNA（Small nucleolar RNAs；snoRNAs）是一类小型RNA分子，可引导核糖体RNA（rRNA）或其他RNA的化学修饰（如甲基化）作用。根据MeSH的分类，此分子属于小核RNA（snRNA）的一种。可分为C/D box与H/ACA box两种。
英语百科
Small nucleolar RNA 核仁小核糖核酸
Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs. There are two main classes of snoRNA, the C/D box snoRNAs, which are associated with methylation, and the H/ACA box snoRNAs, which are associated with pseudouridylation. SnoRNAs are commonly referred to as guide RNAs but should not be confused with the guide RNAs that direct RNA editing in trypanosomes.
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