西蒙尼·马蒂尼（意大利语：Simone Martini；1280年代－1344年）是一位出生于意大利锡耶纳的画家。他在文艺复兴早期的重要成就是极大的发展和影响了未来的国际哥特式艺术风格。

一般来说，马蒂尼被认作是另一位同时期的锡耶纳画家-杜乔·迪·博尼塞尼亚（Duccio di Buoninsegna）的学徒。然而根据文艺复兴晚期的传记作家乔尔乔·瓦萨里（Giorgio Vasari）的著作，马蒂尼则被认为是乔托·迪·邦多纳（Giotto di Bondone）的学徒，而后亦是因为乔托负责制作旧圣伯多禄大教堂马赛克，才有马蒂尼前往罗马绘制同一教堂壁画一事。马蒂尼的妹婿则是另一位同时期的文艺复兴画家Lippo Memmi。

Simone Martini (c.1284 – 1344) was an Italian painter born in Siena. He was a major figure in the development of early Italian painting and greatly influenced the development of the International Gothic style.

It is thought that Martini was a pupil of Duccio di Buoninsegna, the leading Sienese painter of his time. According to late Renaissance art biographer Giorgio Vasari, Simone was instead a pupil of Giotto di Bondone, with whom he went to Rome to paint at the Old St. Peter's Basilica, Giotto also executing a mosaic there. Martini's brother-in-law was the artist Lippo Memmi. Very little documentation of Simone's life survives, and many attributions are debated by art historians.