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单词 Silyl ether
释义

Silyl ether

中文百科

硅醚

硅醚是含有硅原子与烷氧基以共价键键合的一类化合物。其通式为:RRRSi−O−R,其中R为烷基取代基或芳基取代基。硅醚在有机合成当中常用于醇的保护基。RRR基团可以是不同的烃基基团,因此可组合成多样的硅醚。硅醚化合物在保护基化学当中有非常广泛的应用,常用的硅醚有:三甲基硅基 (TMS),叔丁基二苯基硅基(TBDPS),叔丁基二甲基硅基(TBS/TBDMS)和三异丙基硅基(TIPS)。

英语百科

Silyl ether 硅醚

Silyl ethers are a group of chemical compounds which contain a silicon atom covalently bonded to an alkoxy group. The general structure is RRRSi−O−R where R is an alkyl group or an aryl group. Silyl ethers are usually used as protecting groups for alcohols in organic synthesis. Since RRR can be combinations of differing groups which can be varied in order to provide a number of silyl ethers, this group of chemical compounds provides a wide spectrum of selectivity for protecting group chemistry. Common silyl ethers are: trimethylsilyl (TMS), tert-butyldiphenylsilyl (TBDPS), tert-butyldimethylsilyl (TBS/TBDMS) and triisopropylsilyl (TIPS). They are particularly useful because they can be installed and removed very selectively under mild conditions.

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更新时间:2025/6/19 14:46:42