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单词 Short tandem repeat
释义

Short tandem repeat

英语例句库

Allelotype analysis was done at five short tandem repeat markers (D17S855, D17S1322, D17S1323, D17S1326, and D17S1327) in or adjacent to BRCA1 on the recurrent mutation carriers.

对发现携带有相同突变的个体选取5个与BRCA1基因连锁的标记(D17S855、D17S1322、D17S1323、D17S1326和D17S1327)进行单倍型分析。

原声例句
经济学人 Science and technology

At certain specific sites along the chains short strings of bases will repeat, often many times in a row, in what are called short tandem repeats (STRs).

在链条上的某些特定位点, 短串碱基会重复出现,通常连续多次, 这就是所谓的短串联重复序列 (STR)。

中文百科

微卫星 Microsatellite

(重定向自短串联重复)

微卫星英语:Microsatellite,亦称为简单重复串行英语:Simple Sequence Repeats,SSRs)或短串联重复串行英语:short tandem repeats,STRs))是多态性的一种类型。指两个或多个核苷酸重复排列,且不同的重复串行相邻的形式,长度约2到10个碱基对,常见于非编码的内含子中。

由于重复单位及重复次数不同,使其在不同种族,不同人群之间的分布具有很大差异性,构成了STR遗传多态性。不同个体之间在一个同源STR位点的重复次数不同。通过识别基因组在特定位点的特定串行重复,可能创建一个个人基因档案。目前已经有超过10000个STR位点被公开。STR分析法已经成为法医学领域个体识别和亲权鉴定的重要分析方法,可应用于司法案件调查,也就是遗传指纹分析。

英语百科

Microsatellite 微卫星

(重定向自Short tandem repeat)
DNA strand slippage during replication of an STR locus. Boxes symbolize repetitive DNA units. Arrows indicate the direction in which a new DNA strand (white boxes) is being replicated from the template strand (black boxes). Three situations during DNA replication are depicted. (a) Replication of the STR locus has proceeded without a mutation. (b) Replication of the STR locus has led to a gain of one unit owing to a loop in the new strand; the aberrant loop is stabilized by flanking units complementary to the opposite strand. (c) Replication of the STR locus has led to a loss of one unit owing to a loop in the template strand. (Forster et al. 2015)
A partial human STR profile obtained using the Applied Biosystems Identifiler kit

A microsatellite is a tract of repetitive DNA in which certain DNA motifs (ranging in length from 2–5 base pairs) are repeated, typically 5–50 times. Microsatellites occur at thousands of locations in the human genome and they are notable for their high mutation rate and high diversity in the population.

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更新时间:2025/6/21 11:08:34