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单词 Septins
释义

Septins

英语百科

Septin

schematic domain structure of septin polypeptide chain
a) schematic of septin molecule with GTP binding domain to one side and the N and C termini of the polypeptide chain to the other
b) schematic of septin heterohexameric complex (of human septins), where different septins bind to each other via their GTP binding domains or via the N and C termini. Note the symmetry of the complex 
c) schematic how septin complexes could align to form septin filaments
Septins in Saccharomyces cerevisiae (fluorescent micrograph)
• Green: septins (AgSEP7-GFP)
• Red: cell outline (phase contrast)
• Scale bar: 10 μm
Septins in Ashbya gossypii (fluorescent micrograph)
• Green: septins (AgSEP7-GFP)
• Red: cell outline (phase contrast)
• Inlay: 3D reconstruction of a discontinuous septin ring
• Scale bars: 10 μm

Septins are a group of GTP-binding proteins found primarily in eukaryotic cells of fungi and animals, but also in some green algae. Different septins form protein complexes with each other. These complexes can further assemble into filaments, rings and gauzes. Assembled as such, septins function in cells by localizing other proteins, either by providing a scaffold to which proteins can attach, or by preventing diffusion of molecules from one compartment of the cell to another.

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更新时间:2025/6/23 13:07:12