Selective glucocorticoid receptor modulator

（重定向自SEGRA）

The benzopyranoquinoline A 276575, an example of a SEGRA with a more corticosteroid-like structure[6]

Simplified overview of the mechanism of action of a classical glucocorticoid vs the mechanism of action of a SEGRAM

RU 24858, a SEGRA with steroid structure[5]

Selective glucocorticoid receptor modulators (SEGRMs) and selective glucocorticoid receptor agonists (SEGRAs) formerly known as dissociated glucocorticoid receptor agonists (DIGRAs) are a class of experimental drugs designed to share many of the desirable anti-inflammatory, immunosuppressive, or anticancer properties of classical glucocorticoid drugs but with fewer side effects such as skin atrophy. Although preclinical evidence on SEGRAMs’ anti-inflammatory effects are culminating, currently, the efficacy of these SEGRAMs on cancer are largely unknown.

单词	SEGRA
释义	SEGRA 英语百科 Selective glucocorticoid receptor modulator （重定向自SEGRA） Selective glucocorticoid receptor modulators (SEGRMs) and selective glucocorticoid receptor agonists (SEGRAs) formerly known as dissociated glucocorticoid receptor agonists (DIGRAs) are a class of experimental drugs designed to share many of the desirable anti-inflammatory, immunosuppressive, or anticancer properties of classical glucocorticoid drugs but with fewer side effects such as skin atrophy. Although preclinical evidence on SEGRAMs’ anti-inflammatory effects are culminating, currently, the efficacy of these SEGRAMs on cancer are largely unknown.
随便看	alternate sweep的意思 alternate synchronizing的意思 alternate system的意思 alternate system input source的意思 alternate system input source level的意思 alternate system residence device的意思 alternate tape的意思 alternate tension的意思 alternate terminal的意思 alternate test的意思 alternate test for variance heterogeneity的意思 Alternate text的意思 alternate timer的意思 alternate time zone的意思 alternate tooth slot milling cutter的意思 alternate torque的意思 alternate track的意思 alternate track table的意思 alternate track table operation的意思 alternate track table written to disk的意思 alternate transmission的意思 alternate transmission by series的意思 alternate traversing fire的意思 alternate triples的意思 Alternate Trustee的意思