So focal segmental glomerulosclerosis is a type of nephrotic syndrome, that's helpful, but why does the glomerulus develop segmental sclerosis in the first place?

那么局灶节段性肾小球肾炎是肾病综合征的一种，这很有帮助，但肾小球是如何原发性地产生节段性硬化的呢？

Alright, so as a quick recap, focal segmental glomerulosclerosis is a nephrotic syndrome characterized by sclerosis and hyalinosis in some, but not all, glomeruli, and usually only affects part of the glomeruli that it affects.

得！快速回顾一下：局灶节段性肾小球肾炎是一种肾病综合征，以部分肾小球的硬化和玻璃样变为特征，通常只影响肾小球的一小部分。