On the first, we've seen a sea change in public perception.

首先，我们看到，公众观念已经发生了巨大的变化。

With the birth of Sean came a sea change in Lennon's life.

肖恩的降生让列侬的生活发生了翻天覆地的变化。

To ensure that our thirst for drinking water doesn't cause an ecological sea change.

确保我们对饮用水的渴求不会导致海洋生态变化。

The sea changed, the fields changed, the rivers, the villages, and the people changed, yet Egdon remained.

沧海桑田，江河改道，世事兴衰，但埃格敦荒原未曾改变。

With this signing, we mark more than just an agreement. We mark a sea change in international trade.

这场签字仪式标志的不仅仅是一项协议。还标志着国际贸易的重大变化。

But this comes amid really a sea change in the way physicians are prescribing opioids to begin with.

但这是医生在开阿片类药物处方方面巨大改变的开始。

Despite the small crowds, limited in size because of COVID-19, the event marked a sea change in political tone.

尽管由于新冠肺炎的影响，参加就职典礼的人数有限，但这一活动标志着政治基调发生了巨大变化。

The only way to slow the sea change that's started is to stop the release of two oxygen, on carbon.

减缓海洋变化的唯一方法就是停止释放二氧化碳。

Creation is going through a sea change as the balance between consumption and creation changes.

随着消费和创造之间的平衡发生变化，创造正在经历翻天覆地的变化。

" It is a sea change, " says Claire Guthrie Gastanaga, executive director of the American Civil Liberties Union of Virginia.

“这是一场翻天覆地的变化，”弗吉尼亚州美国公民自由联盟的执行董事克莱尔·格思里·加斯塔纳加说。