Sclerostin

Sclerostin is a protein that in humans is encoded by the SOST gene.

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation.

单词	Sclerostin
释义	Sclerostin 原声例句科学60秒-科学美国人 2019年8月合集 Sclerostin is a protein that actually stimulates the breakdown of bone. 骨硬化蛋白是是激发骨骼破坏的蛋白质。科学60秒-科学美国人 2019年8月合集 That irisin, which builds bone, would promote the production of sclerostin, which destroys it, may seem counterintuitive. 而能生成骨骼的鸢尾素，竟然会促进会破坏骨骼的骨硬化蛋白的产生，这似乎违反常理。英语百科 Sclerostin Sclerostin is a protein that in humans is encoded by the SOST gene. Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation.
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