氧化钪（化学式：Sc₂O₃），是钪最常见的氧化物。它是不溶于水的白色粉末，易溶于热酸，但经高温灼烧的氧化钪较难溶解。

氧化钪可借由直接燃烧钪而得：

4 Sc + 3 O₂ → 2 Sc₂O₃

含挥发基的钪化合物经氧化灼烧也可以生成氧化钪。

Scandium(III) oxide, Sc₂O₃, or scandia, is a high melting rare earth oxide. It is used in the preparation of other scandium compounds as well as in high-temperature systems (for its resistance to heat and thermal shock), electronic ceramics, and glass composition (as a helper material).