萨尔贡一世（活动时间公元前20世纪）是阿卡德时期（即沙姆希阿达德一世征服亚述之前）亚述城邦的统治者。 他的地位不应被理解为“国王”，因为他的职位（“伊沙库”）在以前主要是一个管理宗教事务的头衔。然而此时由于亚述商业活动的扩张，伊沙库无疑已具有超过以往的权力。在卡帕多细亚地区发现了一块盖有萨尔贡一世印章的泥板，这也许说明他的权力已经抵达那里。考古学家对萨尔贡一世的其他情况一无所知，虽然他的名字“萨尔贡”很引人注意：在古代西亚，使用这一名字的统治者大多是通过非常手段获得权力的。

Sargon I or Sharru-ken reigned as king of the old-Assyrian Kingdom from ca. 1920 BC to 1881 BC. The name 'Sargon' means 'the king is legitimate' in Akkadian. He is known for his work refortifying Assur. The name "Sargon I" has also been used to refer to Sargon of Akkad, and the Assyrian Sargon may have been named after him. Very little is known about this king.