圣十字若望（西班牙语：San Juan de la Cruz，本名Juan de Yepes Alvarez，1542年6月24日－1591年12月14日）是公教改革的主要人物，西班牙神秘学家，加尔默罗会修士和神父，出生在马德里北部阿维拉（Ávila）附近的小镇丰蒂韦罗斯（Fontiveros），一个改宗基督教的犹太人的家庭之中。

圣十字若望是加尔默罗会的改革者，被认为与圣女大德兰一同创立了赤足加尔默罗会。十字若望以写作着称，他的诗歌及其对灵魂成长的研究，被认为是西班牙神秘文学的巅峰，是西班牙文学的高峰之一. 1726年，本笃十三世封他为圣人。他被列为天主教众位教会圣师之一。

Saint John of the Cross (Spanish:San Juan de la Cruz; 1542 – 14 December 1591), was a major figure of the Counter-Reformation, a Spanish mystic, a Roman Catholic saint, a Carmelite friar and a priest who was born at Fontiveros, Old Castile.

John of the Cross was a reformer in the Carmelite Order of his time and the movement he helped initiate, along with Saint Teresa of Ávila, eventually lead to the establishment of the Discalced Carmelites, though neither he nor Teresa were alive when the two orders separated. He is also known for his writings. Both his poetry and his studies on the growth of the soul are considered the summit of mystical Spanish literature and one of the peaks of all Spanish literature. He was canonized as a saint in 1726 by Pope Benedict XIII. He is one of the thirty-six Doctors of the Church.