圣何塞德瓜尼帕是委内瑞拉的城镇，位于该国东北部安索阿特吉州，是圣何塞德瓜尼帕市的首府，始建于1910年11月14日，海拔高度8米，人口76,398，人口密度为每平方公里97人。

San José de Guanipa (Spanish pronunciation: [saŋ xoˈse ðe ɣwaˈnipa]), also known as El Tigrito, is a city in the state of Anzoátegui, Venezuela. It is the capital of San José de Guanipa Municipality. Officially founded in 1910, it was previously a settlement of the Kali'na people.