沙溪大屠杀（英语：Sand Creek Massacre），又称奇温顿大屠杀（Chivington Massacre），沙溪战役（Battle of Sand Creek），夏安族印第安人屠杀事件（Massacre of Cheyenne Indians），在北美印第安战争期间发生的一起战争犯罪事件。1864年11月29日，约700名隶属于科罗拉多州第三骑兵军团的士兵，无预警袭击了居住在科罗拉多州南方印地安保留地的一个印第安人聚落，当地居住了约200余名夏安族及阿拉巴霍族（Arapaho）居民，这些居民遭到军队的屠杀。这次攻击事件，估计造成70名至163名印第安人死亡，其中三分之二是妇女及小孩。许多印第安人在死亡后遭到肢解，其头皮及身体各部位器官被美军士兵当成战利品，做成饰品来使用。

The Sand Creek massacre (also known as the Chivington massacre, the Battle of Sand Creek or the massacre of Cheyenne Indians) was an atrocity in the American Indian Wars that occurred on November 29, 1864, when a 700-man force of Colorado Territory militia attacked and destroyed a peaceful village of Cheyenne and Arapaho in southeastern Colorado Territory, killing and mutilating an estimated 70–163 Native Americans, about two-thirds of whom were women and children. The location has been designated the Sand Creek Massacre National Historic Site and is administered by the National Park Service.