Samsat (Armenian:Սամոսատ Samosata) is a small town in the Adıyaman Province of Turkey, situated on the upper Euphrates river.

Archaeological research on the hill of Şehremuz in Samsat has uncovered relics from the 7000 BC Paleolithic era; the 5000 BC Neolithic, 3000 BC Chalcolithic and 3000 to 1200 BC Bronze Ages. The ancient city of Ḫaḫḫum (Hittite: Ḫaḫḫa) was located nearby; it is recorded as a source of gold for ancient Sumeria.