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单词 Sabrilex
释义

Sabrilex

英语百科

Vigabatrin

(重定向自Sabrilex)
Crystal Structure (pdb:1OHW) showing vigabatrin binding to specific residues in the active site of GABA-T, based off experiments by Storici et al.[20]

Vigabatrin, also known as gamma-vinyl-GABA, is an antiepileptic drug that inhibits the breakdown of γ-aminobutyric acid (GABA) by acting as a suicide inhibitor of GABA transaminase (GABA-T). It is a structural analog of GABA, but does not bind to GABA receptors. It is sold under the brand name Sabril.

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更新时间:2025/6/20 3:00:28