杂醇油是工业上发酵法制取乙醇、白酒时副产的高级醇类混合物。

无色至黄色、有特殊臭味的油状液体。相对密度0.811～0.832（20 °C）。主要成分为比乙醇碳链更长的高级醇，如戊醇、异戊醇、丁醇、丙醇和庚醇等。有毒，易燃。

一般认为杂醇油较乙醇对人类有更强的毒性和麻醉作用，因此饮用杂醇油含量较高的酒易醉，而且引起头痛。不过最近使用威士忌所做的动物实验没有支持该说法。

Fusel alcohols, also sometimes called fusel oils in Europe, are a mixture of several alcohols (chiefly amyl alcohol) produced as a by-product of alcoholic fermentation. The word fusel is German for "bad liquor".

Whether fusel alcohol contributes or not to hangover symptoms is a matter of scientific debate. A Japanese study in 2003 concluded, "The fusel oil in whisky had no effect on the ethanol-induced emetic response" in Suncus murinus. Additionally, consumption of fusel oils with ethanol suppressed subjects' subsequent taste aversion to alcohol, which suggested subjects' hangover symptoms were lessened, according to the journal.