核糖-5-磷酸（英语：Ribose 5-phosphate）是磷酸戊糖途径的中间体和产物。核糖-5-磷酸是磷酸戊糖途径氧化阶段的最终产物，由核酮糖-5-磷酸异构化而来，根据机体的状态，核糖-5-磷酸也能可逆的变回核酮糖-5-磷酸。

核糖-磷酸焦磷酸激酶将核糖-5-磷酸转化为磷酸核糖焦磷酸。

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药物(A16/C10)、中间产物(k,c/g/r/p/y/i,f/h/s/o/e,a/u,n,m)

Ribose 5-phosphate is both a product and an intermediate of the pentose phosphate pathway. The last step of the oxidative reactions in the pentose phosphate pathway is the production of ribulose 5-phosphate. Depending on the body's state, ribulose 5-phosphate can reversibly isomerize to ribose 5-phosphate. Ribulose 5-phosphate can alternatively undergo a series of isomerizations as well as transaldolations and transketolations that result in the production of other pentose phosphates as well as fructose 6-phosphate and glyceraldehyde 3-phosphate (both intermediates in glycolysis).