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单词 Reverse transcription
释义

Reverse transcription

英语例句库

Alternatively, a new version of a gene can also be created through reverse transcription: during gene expression, the mRNA is copied back into a sequence of DNA that is inserted into the genome.

其二,新的基因复本也可能透过反转录作用,将基因表现出来的mRNA反转录成DNA序列,再插回基因组内,这种现象称为反转录移位(retrotransposition),发生在细胞内称为长散布核因子(LINE)的转位子活动时。

原声例句
Osmosis-防疫 COVID-19

The gold standard for diagnosis of COVID-19 is RT-PCR, or reverse transcription polymerase chain reaction.

诊断COVID-19的金标准是RT-PCR,即逆转录-聚合酶链式反应。

精选英语短文

Reverse transcription turns viral RNA into DNA that polymerase enzymes can then properly amplify.

逆转录将病毒 RNA 转化为 DNA, 然后聚合酶可以适当地扩增该 DNA。

Osmosis-防疫 COVID-19

To confirm the diagnosis, a reverse transcription polymerase chain reaction or RT-PCR test can be done, which can detect very small amounts of viral RNA.

确诊COVID-19感染需要进行逆转录-聚合酶链式反应(RT-PCR)测试,它能够检出非常微量的病毒RNA。

中文百科

逆转录酶 Reverse transcriptase

(重定向自Reverse transcription)
The molecular structure of zidovudine(AZT),a drug used to inhibit HIV reverse transcriptase

逆转录酶是一类存在于部分RNA病毒中具有逆转录活性、能以单链RNA为模板合成DNA的酶。由逆转录酶催化逆转录合成的DNA称为互补DNA(cDNA)。

通常情况下,细胞内的转录是以DNA为模板合成RNA的,所得RNA为信使RNA(mRNA)供蛋白质合成作模板用。而在部分RNA病毒中,要实现自身的扩增,必须具有DNA,因此先由RNA逆转录合成cDNA再由cDNA转录出RNA。

逆转录酶可用于RT-PCR,将RNA转变为DNA后扩增,以获得RNA的串行。

这些活化因子会将反转录病毒里的单股RNA转化成双股cDNA并且将之插入宿主细胞的基因里,在一段时间内繁殖。相同的反应被广泛的应用在实验室中将RNA转换成DNA如分子克隆,RNA测序,聚合酶链反应(PCR),或是DNA微数组。 良好的反转录酶研究物质包含:

英语百科

Reverse transcriptase 逆转录酶

(重定向自Reverse transcription)
Reverse Transcriptase is shown with its finger, palm, and thumb regions. The catalytic amino acids of the RNase H active site and the Polymerase active site are shown in ball and stick form.
The molecular structure of zidovudine (AZT), a drug used to inhibit HIV reverse transcriptase

A reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. It is mainly associated with retroviruses. However, non-retroviruses also use RT (for example, the hepatitis B virus, a member of the Hepadnaviridae, which are dsDNA-RT viruses, while retroviruses are ssRNA viruses). RT inhibitors are widely used as antiretroviral drugs. RT activities are also associated with the replication of chromosome ends (telomerase) and some mobile genetic elements (retrotransposons).

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更新时间:2025/6/17 0:22:19