肾皮质坏死(Renal cortical necrosis、RCN，弥漫性双侧肾皮质坏死(diffuse bilateral renal cortical necrosis、BRCN)、，弥漫性皮质坏死(diffuse cortical necrosis)、急性皮质坏死(acute cortical necrosis)、急性皮质坏死急性肾功能衰竭(acute renal failure with acute cortical necrosis))是急性肾功能衰竭的一种罕见病症。该病症"通常通过显著减少肾动脉灌注(Perfusion)继发于血管痉挛、微血管损伤，或弥散性血管内凝血"，以及由急性肾小管坏死的病理进展所致。经常伴随着产科病症发生、诸如胎盘早剥(Placental abruption)及败血性休克，而且是三倍多见于发展中国家与工业化国家中(占急性肾损伤的病因2％-6％)。

Renal cortical necrosis (RCN, also diffuse bilateral renal cortical necrosis (BRCN), diffuse cortical necrosis, acute cortical necrosis, or acute kidney failure with acute cortical necrosis) is a rare cause of acute kidney failure. The condition is "usually caused by significantly diminished arterial perfusion of the kidneys due to spasms of the feeding arteries, microvascular injury, or disseminated intravascular coagulation" and is the pathological progression of acute tubular necrosis. It is frequently associated with obstetric catastrophes such as abruptio placentae and septic shock, and is three times more common in developing nations versus industrialized nations (2% versus 6% in causes of acute kidney failure).