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单词 Rasagiline
释义

Rasagiline

原声例句
医学英语视频

So, here another useful drugs come into play, namely Selegiline and Rasagiline, which selectively inhibit MAO-B, and Tolcapone, which inhibits COMT.

因此,另一种有用的药物开始发挥作用,即塞来吉林和拉沙吉林,它们选择性地抑制MAO-B和Tolcapone,后者抑制COMT。

中文百科

雷沙吉兰

雷沙吉兰(英文:Rasagiline,AZILECT®),一种单胺氧化酶的不可逆抑制剂,作为早期帕金森病的治疗单药和作为中、晚期帕金森病 L-多巴(Levodopa) 疗法的附加用药。

英语百科

Rasagiline 雷沙吉兰

Rasagiline (Azilect, TVP-1012, N-propargyl-1(R)-aminoindan) is an irreversible inhibitor of monoamine oxidase-B used as a monotherapy to treat symptoms in early Parkinson's disease or as an adjunct therapy in more advanced cases.

The racemic form of the drug was invented by Aspro Nicholas in the early 1979s. Moussa B.H. Youdim identified it as a potential drug for Parkinson's disease, and working with collaborators at Technion – Israel Institute of Technology in Israel and the drug company, Teva Pharmaceutical, identified the R-isomer as the active form of the drug. Teva brought it to market in partnership with Lundbeck in Europe and Eisai in the US and elsewhere. It was approved in Europe in 2005 and in the US in 2006.

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更新时间:2025/6/18 7:04:04