But at present, I don't take rapamycin.

但目前我不服用雷帕霉素。

I've decided to stay away from metformin and rapamycin.

我决定远离二甲双胍和雷帕霉素。

Like rapamycin, it extends the lifespans of healthy mice.

与雷帕霉素一样，它可以延长健康小鼠的寿命。

But its side-effects, including anaemia and an insensitivity to insulin, make rapamycin ill-suited for widespread use.

但其副作用，包括贫血和对胰岛素不敏感，使得雷帕霉素不适合广泛使用。

Not surprisingly, metformin is also used off-label, probably more widely than rapamycin.

毫不奇怪，二甲双胍也被用于标签外，可能比雷帕霉素更广泛。

They do this by combining to form a hamartin-tuberin protein complex, which binds to and inhibit another protein called mechanistic Target Of Rapamycin, or mTOR.

这两个蛋白结合在一起，形成hamartin-tuberin蛋白复合体；并与另一种蛋白：雷帕霉素靶蛋白（mTOR）结合并抑制它。

One is metformin, which has been approved for use against type-2 diabetes; another is rapamycin, an immunosuppressant used in organ transplants.

其中之一是二甲双胍，已被批准用于治疗 2 型糖尿病；另一种是雷帕霉素，一种用于器官移植的免疫抑制剂。

What is more, rapamycin, the effects of which give mtorc1 its name, turns out to lengthen the lives of lab animals even though it curbs their immune responses.

更重要的是，雷帕霉素（mtorc1 的名字来源于雷帕霉素）被证明可以延长实验动物的寿命，尽管它会抑制实验动物的免疫反应。

The complex of proteins which gives it its name first came to attention because an immune suppressant called rapamycin has a strong effect on it: hence " mechanistic target of rapamycin complex 1" .

这种蛋白质复合物因其名字而首次引起人们的关注，因为一种名为雷帕霉素的免疫抑制剂对其具有很强的作用：因此被称为“雷帕霉素复合物 1 的机械靶点”。